MASHPEE, MASSACHUSETTS — A violent collision at the intersection of Route 151 and Old Barnstable Road left at least two victims seriously injured late Wednesday night. The crash occurred around 10 p.m.

Both vehicles were heavily damaged, forcing firefighters to battle twisted metal while cutting trapped victims from the wreckage.

One badly injured patient was rushed to Falmouth Hospital and loaded onto a MedFlight helicopter for an emergency airlift to an off-Cape trauma center. A second patient was sped by ambulance toward Cape Cod Hospital after a second MedFlight helicopter was requested — only to be canceled for the time being as ground transport continued to the emergency room.  (NOTE: There was a second MedFlight helicopter that took off from the airport in Hyannis this morning at around 2:30 a.m… but it remains uncertain whether or not it was for the same crash.) At least one additional ambulance responded to the Route 151 scene to treat a third patient with less serious injuries. [DEVELOPING]

Mashpee police summoned crash reconstruction specialists to determine the exact cause of the devastating smash-up. According to radio transmissions, both seriously injured patients were male, ages estimated from 20 into their 30s, both suffering injuries described as “multi-system trauma.” No further details on the victims’ conditions have been released.

The following HN Video contains footage from the scene, along with some Mashpee Fire Department radio transmissions…

[HN VIDEO  –  PRESS PLAY]

Mashpee Police Update 5/14/26: 

On May 13th at approximately 10:05 PM, the Mashpee Police Department and Mashpee Fire/Rescue responded to the intersection of Route 151 and Old Barnstable Road for the report of a rear end motor vehicle crash involving 2 vehicles. The crash occurred in the westbound travel lane of Rte. 151.

Upon arrival patrol units observed 2 vehicles that were heavily damaged. One vehicle sustained heavy rear end damage, and the other vehicle sustained heavy front-end damage as a result of the crash.

There was a total of 4 occupants in the vehicle that was struck from behind. Two occupants from that vehicle had to be extricated by Mashpee Fire/Rescue. All 4 occupants were transported to area hospitals. One occupant was later MedFlighted to Rhode Island Hospital with serious injuries.

The operator and sole occupant of the second vehicle involved was treated on scene. Falmouth Fire/Rescue also assisted.

This crash remains under investigation by the Mashpee Police Department and the Cape Cod Regional Law Enforcement Council Crash Reconstruction Team.

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